Total Synthesis Paper

For the final assignment, I will provide each of you with a total synthesis paper to read and evaluate. You will write a short, informal paper (~3-4 pages) containing the following sections (numbered, please):             • Brief bio of the researchers             • Importance of the work, history, previous work – must contain at least one image taken from a previous synthesis or study of the molecule.             • General plan and key step(s) – must contain discussion of the core concept(s) behind the key steps including at least one original ChemDraw composition.             • Discussion on the success or failures of the approach, including discussion of the execution of the key step.             • One additional reaction you had never seen before and found interesting, including a mechanism for that reaction (can be drawn by you or lifted from a previous paper).             • References – must use at least 4 original research papers beyond the assigned one (so at least 5 total). No more than 1 paper can be cited in section 1 alone.   https://pubs.acs.org/doi/10.1021/acs.orglett.8b02478 (Total Synthesis of Repraesentin F and Configuration Reassignment by a Gold(I)-Catalyzed Cyclization Cascade)